Allostasis, Homeostasis, and the Costs of Physiological AdaptationJay Schulkin Cambridge University Press, 25 okt. 2004 - 372 sidor The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology. |
Innehåll
Principles of Allostasis Optimal Design Predictive Regulation Pathophysiology and Rational Therapeutics | 17 |
Protective and Damaging Effects of the Mediators of Stress and Adaptation Allostasis and Allostatic Load | 65 |
Merging of the Homeostat Theory with the Concept of Allostatic Load | 99 |
Operationalizing Allostatic Load | 113 |
Drug Addiction and Allostasis | 150 |
Adaptive Fear Allostasis and the Pathology of Anxiety and Depression | 164 |
A Chronobiological Perspective on Allostasis and its Application to Shift Work | 228 |
Allostatic Load and Life Cycles Implications for Neuroendocrine Control Mechanisms | 302 |
Viability as Opposed to Stability An Evolutionary Perspective on Physiological Regulation | 343 |
| 365 | |
Andra upplagor - Visa alla
Allostasis, Homeostasis, and the Costs of Physiological Adaptation Jay Schulkin Begränsad förhandsgranskning - 2004 |
Allostasis, Homeostasis, and the Costs of Physiological Adaptation Jay Schulkin Ingen förhandsgranskning - 2012 |
Vanliga ord och fraser
activity adaptation adrenal allostasis allostatic load allostatic load scores allostatic overload type allostatic regulation amygdala animals anxiety associated behavior biological biomarkers blood pressure body temperature Brain Res calcium cardiovascular catecholamines cells central nucleus challenges changes circadian rhythms Clin concept of allostasis corticosterone corticotropin-releasing hormone cortisol cycle cytokines depression disease disorders drug dysregulation effector effects elevated ELHS emotional environment environmental example fear conditioning feedback function gene glucocorticoids glucocorticosteroids glucose hippocampus history stage homeostasis homeostatic hormone human hypertension hypothalamus immune increased individual insulin Koob lesions levels LHSs McEwen mechanisms mediators metabolic Mrosovsky negative nervous system neural neuroendocrine neurons Neurosci night normal organism pathology pathways Physiol physiological regulation prediction prefrontal cortex processes protein rats receptors regulatory response rheostasis role Rosen Schulkin setpoint shift workers shiftwork signals sleep social Sterling and Eyer stimuli stressor stria terminalis studies suprachiasmatic suprachiasmatic nucleus tion trigger Wingfield
Populära avsnitt
Sida 13 - Bauman, DE and WB Currie. 1980. Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis.
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