Neurogenetics: Genetic Approaches to the Nervous System

abnormal Acad acid adenylate cyclase adult allele animals assay autosomal axons behavior biochemical genetic Biol brain catecholamines cell types cerebellar cerebellum chimeras chromosome ciliary clinical clone component COMT culture cyclase activity defect deficiency depolarization depression disease dorsal Drosophila melanogaster embryo enzyme enzyme activity fibroblasts Figure frequency function ganglia ganglion ganglioside gene genotype granule cells grasshoppers HPRT human hybrids identified neurons inactivation inherited interneurons isogenic Jimpy Kung large ocellar interneurons lesion linkage lipidoses lipids male MAO activity marker membrane metabolism mice molecular mosaics motorneurons mouse mutant myelin Natl nerve nervous system neural neuroblastoma neuroblasts neurologic neurons neuropil neurotransmitter normal norpA paramecia Paramecium patients phenotype photoreceptor Physiol pigment plasma population probands Proc protein Purkinje cells Quaking receptor potential relatives somata specific speech ẞ-galactosidase stimulus structure stuttering substrate Tay-Sachs disease temperature tion tissue variability variation ventral visual wild type wild-type