AutoantibodiesYehuda Shoenfeld, M. Eric Gershwin, M.E. Gershwin, Pier Luigi Meroni Elsevier, 13 okt. 2011 - 872 sidor Autoantibodies was published and presented in November 2006 at the International Congress of Autoimmunity in Sorrento, a small town in Campania, Italy. The Congress also celebrated the 100th anniversary of the first routine test for autoantibodies. An autoantibody is a type of antibody that is produced by the immune system and that fights one or more of a person’s own proteins. These autoantibodies cause autoimmune diseases such as lupus erythematosus. The authors and editors of this book provide a critical review of autoantibodies and their primary functions. They cite a number of major developments in the field of autoantibodies, including the detection of autoantibodies in which a healthy person is a carrier; the discovery that autoantibodies can be both pathogenic and protective in some cases; and the development of a device that will help monitor and detect a specific autoantibody using a small amount of serum and proteomic arrays. Aside from the pathogenic and protective autoantibodies, the book also discusses irrelevant autoantibodies, as these may be relevant for future research. It also addresses the importance of the autoantibodies in a person’s body. Clinical physicians, as well as scientists interested in the significance of autoantibodies in the human body, will find this book relevant. It will also be of interest to those who suffer from an autoimmune disease.
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Innehåll
Part II Allergic Disease Autoantibodies | 83 |
Part III Antineutrophil Antibodies | 93 |
Antinuclear Antibodies | 127 |
Part V Autoantibodies to Biologic FactorsStructures | 255 |
Part VI Cardiac Autoantibodies | 339 |
Part VII Endocrine Autoantibodies | 367 |
Part VIII GI and Liver Autoantibodies | 415 |
Part IX Hematologic Autoantibodies | 493 |
Part XI Neurological System Autoantibodies | 567 |
Part XII Rheumatic Disease Autoantibodies | 667 |
Part XIII Skin Disease Autoantibodies | 763 |
Part XIV Unique Clinical Situations | 781 |
Part XV Future Directions | 815 |
827 | |
Color Plates | 839 |
Part X Kidney Autoantibodies | 545 |
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Autoantibodies Yehuda Shoenfeld,Pier Luigi Meroni,M. Eric Gershwin Begränsad förhandsgranskning - 2013 |
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2/e Copyright 2GPI affinity alpha-fodrin amino acids ANCA anti anti-DNA anti-dsDNA anti-tTG antibodies antigen antiphospholipid apoptosis assay associated atherosclerosis autoantibodies autoantigens autoimmune diseases B.V. All rights binding C3NeF cancer cells Clin CLINICAL UTILITY coeliac disease collagen correlation cytokines cytoplasmic diabetes diagnostic disease activity domain ELISA enzyme epitopes expressed factor function FVIII gangliosides gene genetic hepatitis histone HISTORICAL NOTES human identified idiotypes IgG1 immune complexes immune response immunoblotting immunofluorescence immunoglobulin Immunol indirect immunofluorescence induced markers membrane MESSAGES REFERENCES ABSTRACT mice molecular molecules monoclonal neurological normal nuclear nucleosome paraneoplastic pathogenic role patients peptides plasma platelet positive present prevalence protein purified reactivity receptor recombinant reported rheumatoid arthritis scleroderma sclerosis sensitivity sera serum Sjögren’s syndrome specific staining studies subunits systemic lupus erythematosus T1DM TAKE-HOME MESSAGES REFERENCES target thrombosis thyroid tissue titers tumor vasculitis VGCC vitro
Populära avsnitt
Sida 18 - Fujinami RS, Oldstone MBA, Wroblewska Z, Frankel ME, Koprowski H. Molecular mimicry in virus infection: Crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments. Proc Natl Acad Sci USA 1983;80:2346-50. 106. Fujinami RS, Oldstone MBA. "Cross-reaction of measles virus phosphoprotein with a human intermediate filament: molecular mimicry during virus infection.
Sida 59 - Arbuckle MR, McClain MT, Rubertone MV, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003;349:1526-1533.
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