The Vascular Smooth Muscle Cell: Molecular and Biological Responses to the Extracellular MatrixElsevier, 24 okt. 1995 - 410 sidor In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells.
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Innehåll
1 | |
17 | |
Chapter 3 Integrins Cytoskeletal and Extracellular Matrix Proteins in Developing Smooth Muscle Cells of Human Aorta | 37 |
Chapter 4 Relevance of Smooth Muscle Replication and Development to Vascular Disease | 81 |
Chapter 5 Smooth Muscle Gene Expression during Developmental Maturation | 141 |
Molecular Identity of Smooth Muscle Cells Overview | 163 |
Smooth Muscle Cell Function from the Clinical Perspective Overview | 267 |
Epilogue | 401 |
403 | |
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The Vascular Smooth Muscle Cell: Molecular and Biological Responses to the ... Stephen M. Schwartz,Robert P. Mecham Ingen förhandsgranskning - 1995 |
The Vascular Smooth Muscle Cell: Molecular and Biological Responses to the ... Stephen M. Schwartz,Robert P. Mecham Ingen förhandsgranskning - 1995 |
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Acad actin activity adult alternative splicing angioplasty angiotensin antibodies aorta aortic smooth muscle arterial smooth muscle atherosclerosis Campbell cardiac cDNA Cell Biol Chem Circ cloning Clowes contractile coronary culture cytoskeleton desmin developmental differentiation ductus arteriosus elastin endothelial cells endothelium exon extracellular matrix fetal fibroblasts fibronectin filaments Gabbiani gene expression Glukhova growth factor heparin human hypertension inhibition inhibitors injury integrin intimal smooth muscle intimal thickening isoforms Koteliansky laminin lesions lumen markers medial smooth muscle MEF2 mitogenic molecules mouse mRNA muscle cell proliferation muscle cell replication muscle myosin heavy MyoD myofibroblasts myosin heavy chain neointimal nonmuscle normal o-smooth muscle actin Pathol PDGF phenotype plaque proteins rabbit receptor regulation Reidy restenosis role Schwartz sequence serum Skalli skeletal muscle SMCs smooth mus smooth muscle cells smooth muscle myosin smooth muscle o-actin smooth muscle-specific studies tion tissue transcription factor vascular smooth muscle vinculin vitro vivo